Related Experiment Video
Updated: Aug 8, 2026

Studying the Hypothalamic Insulin Signal to Peripheral Glucose Intolerance with a Continuous Drug Infusion System into the Mouse Brain
Published on: January 4, 2018
Recurrent episodes of hypoglycemia as an initial presentation of pituitary stalk interruption syndrome: A case report
Radhika Thagunna1, Shivali Rao1, Binit Bajracharya2
1Department of Radiology, Tribhuvan University Teaching Hospital, Kathmandu, Nepal.
Abstract:
Pituitary stalk interruption syndrome is a rare, congenital endocrine disorder of hypopituitarism. It has highly variable clinical presentation depending on the extent and type of hormonal deficiency and age at presentation, with growth hormone deficiency being the most common manifestation. Growth hormone plays an important role in maintaining normal blood glucose levels during stress or fasting, by stimulating hepatic gluconeogenesis and lipolysis. Therefore, hypoglycemia should alert us to a possibility of growth hormone deficiency necessitating imaging and facilitating early diagnosis of pituitary stalk interruption syndrome.
Related Concept Videos
Hypoglycemia and Glucagon
Hypoglycemia
Type I Diabetes III: Clinical Manifestations
Pathophysiology of Diabetes
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility, suggesting a...
Hyperglycemia
Type II Diabetes II: Pathophysiology

