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Updated: Aug 10, 2026
A Neonatal Mouse Spinal Cord Compression Injury Model
Published on: March 27, 2016
Posterior Mediastinal Yolk Sac Tumor with Spinal Cord Compression in a Toddler: A Rare Case Report with Long-term
Shilpa Sharma1, Rafey Abdul Rahman2, Venkateswaran K Iyer3
1Department of Pediatric Surgery, AIIMS, New Delhi, India.
Insights
Posterior mediastinal yolk sac tumors (YSTs) are rare in children and can cause spinal cord compression. Prompt diagnosis and treatment, including chemotherapy and surgery, can lead to recovery and remission.
Area of Science:
- Pediatric Oncology
- Neuro-oncology
- Surgical Oncology
Background:
- Posterior mediastinal yolk sac tumors (YSTs) are rare germ cell tumors.
- Spinal cord compression in children secondary to mediastinal tumors is uncommon.
- Yolk sac tumors can exhibit aggressive behavior and metastasis.
Abstract:
Posterior mediastinal yolk sac tumors (YSTs) with spinal cord compression are exceedingly rare in children. We report a 3-year-old boy with paraplegia due to a posterior mediastinal YST with intraspinal extension. Neoadjuvant chemotherapy followed by surgery led to neurological recovery and long-term remission, highlighting diagnostic and therapeutic challenges.
