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Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates
Published on: March 20, 2015
Surface modifications of nanomaterials used for surface-enhanced Raman scattering measurements
Jan Krajczewski1, Andrzej Kudelski1
1University of Warsaw, Faculty of Chemistry, Pasteura 1 Str., PL 02-093 Warsaw, Poland.
Summary
Surface-enhanced Raman scattering (SERS) substrates can be modified with coatings to enhance functionality. These modifications, like metal or oxide layers, enable new applications despite potentially reducing the SERS enhancement factor.
Area of Science:
- Materials Science
- Spectroscopy
- Nanotechnology
Background:
- Surface-enhanced Raman scattering (SERS) significantly amplifies Raman signals from adsorbed molecules.
- SERS substrates are often coated, which can increase analyte-nanostructure distance and decrease enhancement.
- Coatings, however, can impart novel functionalities to SERS nanomaterials.
Purpose of the Study:
- To review methods for modifying SERS substrate surfaces.
- To discuss new possibilities offered by these surface modifications.
Main Methods:
- Deposition of metal layers onto SERS substrates.
- Deposition of oxide layers onto SERS substrates.
- Attachment of macromolecules to SERS substrates.
Main Results:
- Surface modifications can introduce new functions like selective analyte capture.
- Modified substrates allow SERS measurements on non-SERS-active metal layers.
- Review covers diverse modification techniques and their functional outcomes.
Conclusions:
- Modifying SERS substrates with coatings offers new functionalities and applications.
- Despite potential enhancement factor reduction, coatings provide valuable capabilities for SERS nanomaterials.
