Related Experiment Video

Updated: Aug 9, 2026

Assays for the Degradation of Misfolded Proteins in Cells
10:56

Assays for the Degradation of Misfolded Proteins in Cells

Published on: August 28, 2016

p62/SQSTM1-KEAP1 complex prevents clearance of ubiquitinated Z alpha-1 antitrypsin and aggravates liver

Nunzia Pastore1, Sergio Attanasio2, Francesco Annunziata2

  • 1Telethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, Naples, Italy; Department of Translational Medicine, Medical Genetics, Federico II University of Naples, Naples, Italy.

The Journal of Biological Chemistry
|August 7, 2026
PubMed

Keywords:
AATDKEAP1NRF2p62/SQSTM1proteostasis

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