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Integrating the Metaverse Into Medical Practice: A Systematic Review of Its Potential and Applications
Marsa Gholamzadeh1, Shahryar Naji1, Elmira Khakvatan1
1Health Information Management and Medical Informatics Department, School of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran, tums.ac.ir.
International Journal of Telemedicine and Applications
|August 8, 2026
Summary
The metaverse in healthcare is emerging, with current applications focused on system design for education and mental health. Evidence of clinical effectiveness is limited, highlighting a need for more research.
Area of Science:
- Digital Health and Medical Technology
- Virtual and Augmented Reality Applications in Medicine
- Healthcare Innovation
Background:
- The metaverse, a convergence of virtual and physical realities, offers immersive experiences with revolutionary potential for medical care.
- Current understanding of metaverse applications in healthcare is evolving, necessitating a review of existing research and development.
Purpose of the Study:
- To explore and synthesize current applications of metaverse technology across diverse medical specialties.
- To identify trends, implementation frameworks, and target groups for metaverse interventions in healthcare.
Main Methods:
- Systematic literature search conducted across five major electronic databases (Web of Science, PubMed, Scopus, CINAHL, IEEE) following PRISMA guidelines.
- Qualitative analysis of 46 studies published between 2022 and 2024, focusing on medical domains, metaverse types, implementation, and target populations.
Main Results:
- Metaverse applications are prominent in medical education (15.22%), mental health (13.04%), and rehabilitation (13.04%), with virtual worlds being the most common type (50.00%).
- Research predominantly focuses on system design and development, targeting patients (47.06%) and medical students (23.53%) for treatment, education, and follow-up.
- South Korea leads in publications (24%), indicating a regional focus in current research.
Conclusions:
- Metaverse applications in healthcare are nascent, with current efforts centered on system design and feasibility rather than established clinical outcomes.
- Limited evidence of clinical effectiveness exists, despite the integration of emerging technologies like AI and blockchain.
- This review provides a roadmap for evidence-based advancement in understudied clinical areas within the metaverse.
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