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Updated: Aug 10, 2026
A Postoperative Evaluation Guideline for Computer-Assisted Reconstruction of the Mandible
Published on: January 28, 2020
Radiomic analysis of pathologically confirmed mandibular osteoradionecrosis to identify cases with associated
Olivier Ozcan1, Remy Laluc2, Aline Carsin-Vue3
1Department of Radiation Oncology, Institut Godinot, Reims, France.
None:
Differentiating mandibular osteoradionecrosis (ORN) from tumor recurrence remains challenging on preoperative imaging. We conducted a multicenter retrospective study including 24 patients with histologically confirmed ORN who underwent surgery and had preoperative CT available. Radiomic features were extracted using an IBSI-compliant pipeline and compared between pure ORN (n = 21) and ORN with recurrence (n = 3). Three features showed nominal uncorrected differences between groups. Given the rarity of histologically confirmed recurrence, this study was designed as an exploratory hypothesis-generating analysis. These findings suggest that CT radiomics may capture subtle imaging differences and warrant validation in larger cohorts.