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Early outcomes of online adaptive MR-guided SBRT for localized prostate cancer: a prospective study
Abrahams Ocanto1,2, María González1,2, Macarena Teja1,2
1Department of Radiation Oncology, Hospital Universitario Vithas La Milagrosa, GenesisCare, 28010 Madrid, Spain.
Clinical and Translational Radiation Oncology
|August 8, 2026
Abstract:
•Online adaptive MR-guided SBRT demonstrated low rates of acute side effects grade ≥ 2 toxicity (3% GU, 0% GI).•Daily adaptive planning with 2-mm margins enabled favorable tolerability outcomes without hydrogel spacers.•Patient-reported outcomes showed minimal impact on urinary, bowel, and global quality of life.•No biochemical failures were observed at 1-year follow-up.•MRgRT may improve safety profiles beyond margin reduction through adaptive workflows.
