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Ensuring Knowledge Transfer: The Critical Role of "What-If" Discussions in Virtual Patient Simulation
Zhien Li1, Maryam Asoodar1, Tom Keulers2
1Department of Educational Development & Research, School of Health Professions Education, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands.
Perspectives on Medical Education
|August 8, 2026
Summary
This study shows that integrating virtual patients (VPs) with role modelling and "what-if" discussions significantly improves medical students' ability to apply knowledge to new cases. The intervention enhanced both near and far transfer of learning in cancer treatment education.
Area of Science:
- Medical Education
- Health Professions Education
- Clinical Reasoning
Background:
- Virtual Patient (VP) systems are valuable tools in medical education.
- Evidence on VP effectiveness for near and far transfer of learning is limited.
- This study explored an intervention integrating VPs with role modelling, varied case practices, and "what-if" discussions.
Purpose of the Study:
- To measure medical students' experience with the VP intervention.
- To assess improvements in performance scores on near- and far-transfer cases.
- To explore how and why the intervention enhances knowledge transfer.
Main Methods:
- An exploratory mixed-methods study with 21 undergraduate medical students.
- Intervention included role modelling, authentic case practice, and "what-if" discussions.
- Data collected via surveys, pre/post-assessments (near/far transfer cases), and group interviews.
Main Results:
- Students reported positive perceptions of role modelling, case practices, and discussions.
- Significant improvements observed in tumour-stage reasoning for near and far transfer (p < .001).
- Significant improvements noted in initial patient impressions (p = .007) and total scores (p = .018) for far transfer.
Conclusions:
- The VP intervention positively impacted student experience and significantly enhanced near and far transfer of learning.
- Reflection via "what-if" discussions was key to deepening understanding and enabling knowledge transfer.
- The study suggests this integrated approach effectively supports the application of medical knowledge in diverse clinical scenarios.