The Open Data Commons for Traumatic Brain Injury: An Interagency Community Platform for Pre-Clinical Data Management...

Area of Science:

• Neuroscience
• Biomedical Informatics
• Data Science

Background:

• The Open Data Commons for Traumatic Brain Injury (ODC-TBI.org) was established in 2018 to facilitate data sharing in pre-clinical TBI research.
• Advancements in data science and AI underscore the need for high-quality, FAIR (Findable, Accessible, Interoperable, and Reusable) data sharing to accelerate discovery and address reproducibility issues in translational research.
• Specialist repositories like ODC-TBI are crucial for biomedical communities to define domain-specific data sharing requirements, aligning with funder and journal mandates.

Purpose of the Study:

• To describe the current organization, operation, and governance of the ODC-TBI.
• To provide an overview of public datasets, analyzing data sharing practices, including the use of common data elements (CDEs) and ancillary practices like linking to publications and data citation.
• To examine the impact of ODC-TBI through download statistics and data reuse in published studies, identifying areas for improvement in outreach and training.

Main Methods:

• Descriptive analysis of the ODC-TBI repository's structure, policies, and operational framework.
• Detailed examination of publicly available datasets, focusing on data standards (CDEs) and metadata completeness.
• Statistical analysis of user engagement, dataset downloads, and citation metrics to assess repository impact and data reuse.

Main Results:

• ODC-TBI is the recognized repository for pre-clinical TBI research, supported by the National Institute on Neurological Disorders and Stroke and integrated into the PRECISE-TBI project.
• Since 2022, broad outreach via PRECISE-TBI has led to a substantial increase in users, uploaded datasets, and public data releases.
• An Editorial Board has been established for community oversight, promoting standards like CDEs; analysis shows progress in data sharing but highlights needs for enhanced outreach and training.

Conclusions:

• The ODC-TBI has experienced significant growth and increased data sharing activity, driven by the PRECISE-TBI initiative and community engagement.
• The repository serves as a vital infrastructure component for pre-clinical TBI research, promoting rigor and reproducibility.
• Continued efforts in outreach, communication, and training are essential to cultivate a comprehensive culture of data sharing within the pre-clinical TBI research community.