Related Experiment Video

Updated: Aug 10, 2026

Investigating the Pathogenesis of MYH7 Mutation Gly823Glu in Familial Hypertrophic Cardiomyopathy using a Mouse Model
03:45

Investigating the Pathogenesis of MYH7 Mutation Gly823Glu in Familial Hypertrophic Cardiomyopathy using a Mouse Model

Published on: August 8, 2022

Compound MYH7 Mutations: Risk Stratification Challenges in an Affected Family

Arafat Hammad1, Amy Yeung1, Howard Goldschmidt2

  • 1Department of Internal Medicine, Valley Health System/Icahn School of Medicine at Mount Sinai, Paramus, New Jersey, USA.

JACC. Case Reports
|August 8, 2026
PubMed
Summary

Genetic testing and cardiac MRI aid sudden cardiac death risk stratification in hypertrophic cardiomyopathy (HCM) when standard markers are unclear. Family-based genetic evaluation is crucial for personalized risk assessment.

Keywords:
MYH7hypertrophic cardiomyopathyimplantable cardioverter-defibrillatorlate gadolinium enhancementrisk stratificationsudden cardiac death

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