Related Experiment Video

Updated: Aug 10, 2026

Ablation of Ischemic Ventricular Tachycardia Using a Multipolar Catheter and 3-dimensional Mapping System for High-density Electro-anatomical Reconstruction
06:57

Ablation of Ischemic Ventricular Tachycardia Using a Multipolar Catheter and 3-dimensional Mapping System for High-density Electro-anatomical Reconstruction

Published on: January 31, 2019

Cardioneuroablation for Vagally Mediated Coronary Artery Spasm With High-Grade Atrioventricular Block and Vasovagal

Hongyi Zhao1, Zemin Yang2, Bohua Li2

  • 1Department of Cardiology, Renmin Hospital of Wuhan University, Hubei Key Laboratory of Cardiology, Cardiovascular Research Institute, Wuhan University, Wuhan, PR China.

JACC. Case Reports
|August 8, 2026
PubMed

Insights

Coronary artery spasm (CAS) can cause syncope due to vagal overactivity. Cardioneuroablation (CNA) successfully treated a patient with refractory, vagally mediated CAS and syncope.

Area of Science:

  • Cardiology
  • Autonomic Nervous System Research
  • Electrophysiology

Background:

  • Coronary artery spasm (CAS) is linked to ischemia, arrhythmias, and syncope, often without obstructive coronary disease.
  • A parasympathetic-dominant phenotype is increasingly recognized as a cause of CAS and related symptoms.
  • Refractory syncope can significantly impact patient quality of life.
Abstract

Keywords:
atrioventricular blockcardioneuroablationcoronary artery spasmganglionated plexusvagal responsevasovagal syncope

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