Related Experiment Video
Updated: Aug 10, 2026

Evaluating Therapeutic Interventions in the SHIP-deficient Mouse Model of Crohn Disease-like Ileitis and Fibrosis
Published on: October 14, 2025
Inflammatory Bowel Disease in Spain: Scientific Output, Collaboration and Research Characteristics
Beatriz Mateos1, Isabella Dotti2, Javier Conde-Aranda3
1Integrative Genomics Lab, Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, 48160 Derio, Spain.
Spanish inflammatory bowel disease (IBD) research shows sustained activity across clinical, translational, and basic science. While productivity varies regionally, international collaboration is extensive, though gender disparities in leadership persist.
Area of Science:
- Gastroenterology and Hepatology
- Immunology
- Biomedical Research
Background:
- Spanish Inflammatory Bowel Disease (IBD) research has grown significantly but lacks comprehensive evaluation of scientific output and international congress representation.
- This study assesses recent Spanish contributions to clinical, translational, and basic IBD research.
Purpose of the Study:
- To provide a descriptive overview of Spanish IBD research contributions.
- To analyze scientific leadership, regional distribution, methodologies, topics, and gender representation in IBD research.
Main Methods:
- Systematic retrieval and classification of 1,361 Spanish publications (2020-2024) from PubMed.
- Evaluation of 638 accepted communications at European Crohn's and Colitis Organisation congresses (2019-2024).
- Analysis included study type, research topic, methodology, journal quartile, authorship, presentation format, leadership, gender, and region.
Main Results:
- 61.3% of publications were clinical; 38.7% were basic/translational.
- 84.5% of publications were in Q1/Q2 journals; 30.6% of Q1 articles were in top-decile journals.
- Activity concentrated in Catalonia and Madrid; women showed higher leadership in basic/translational research.
Conclusions:
- Spanish IBD research demonstrates sustained activity and broad scope.
- Significant regional disparities in productivity and persistent gender disparities in leadership were observed.
- Extensive international collaboration characterizes the current landscape of Spanish IBD research.
Related Concept Videos
Inflammatory Bowel Disease III: Crohn's Disease
Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...
Inflammatory Bowel Disease II: Ulcerative Colitis
Inflammatory Bowel Disease IV: Clinical Manifestations
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
