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The Italian Spine Trauma Registry: design and rationale of a prospective nationwide multicenter study on surgically
Rossella Rispoli1, Simona Bistazzoni2, Fabio Savoldi3
1Department of Spine and Spinal Cord Surgery, University Hospital of Udine, Udine, Italy. rossella.rispoli@asufc.sanita.fvg.it.
Study Design:
Prospective, nationwide, multicenter observational cohort registry with first-year implementation data.
Objectives:
To describe the design and rationale of the Italian Spine Trauma Registry (TVMit) and assess the feasibility of standardized nationwide recruitment and longitudinal data collection in surgically treated spinal trauma.
Setting:
Forty-eight neurosurgical centers across Italy.
Methods:
Adults aged ≥ 16 years undergoing surgery for traumatic spinal column and/or spinal cord injury are prospectively enrolled from 2025 to 2034. Standardized data include demographics, injury characteristics, neurological status, surgical timing and technique, perioperative management, complications, rehabilitation, and Patient-Reported Outcome Spine Trauma (PROST), with follow-up at 3, 12, and 24 months.
Results:
During the first year, 673 participants were enrolled. Lumbar injuries were most frequent (46.2%), followed by thoracic (30.6%), subaxial cervical (15.0%), and upper cervical injuries (8.0%). Surgery within 48 h was more frequent for subaxial cervical injuries (46.5%), and posterior approaches predominated at upper cervical, thoracic, and lumbar levels.
Conclusions:
TVMit has established a feasible national prospective platform for standardized real-world data collection in surgically managed spinal trauma. Longitudinal neurological and patient-reported outcomes will support benchmarking, comparative effectiveness research, and future predictive modeling.
