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Updated: Aug 10, 2026
A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
Published on: August 12, 2020
First Report on Neonatal Isolated Submandibular Suppurative Sialadenitis in Preterm Triplet Girls
Patrick Morhart1, Sergio Antonio Maravilla-Galdamez1, Petros Strempas1
1Department of Neonatology, Childrens' Hospital, Klinikum Bayreuth, Preuschwitzer Str. 101, 95445, Bayreuth, Germany.
Abstract:
Neonatal isolated submandibular suppurative sialadenitis (NISSS) is a rare condition. We present a case of NISSS caused by Staphylococcus aureus (S. aureus) in premature triplet girls born at 28 + 1 weeks of gestation. Mother's milk culture tested positive for S. aureus, which is presumed to be the potential contributing factor of the infection. The first symptoms appeared in one of the girls at 31 days of age, followed by her sisters at 34 and 36 days of age, respectively. A search of the PubMed/Medline, ScienceDirect and Web of Science databases revealed that this is the first reported case of NISSS in triplets. We defined risk factors like an immature immune system, prolonged orogastric feeding and antidiuretic therapy for developing NISSS in neonates.
