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BEAT-B Study (Behavior, Aspirations, and Treatment Needs): A Mixed-Methods Study of Patient Values, Preferences, and

Manya Prasad1, Tushar Prabhakar1, Priyanka Shenoy1

  • 1Institute of Liver and Biliary Sciences, New Delhi, India.

Journal of Gastroenterology and Hepatology
|August 10, 2026
PubMed

Insights

Understanding patient values is key to improving chronic hepatitis B (HBV) treatment uptake. Factors like education, family support, and clear guidance significantly impact adherence to HBV therapy.

Area of Science:

  • Public Health
  • Infectious Diseases
  • Health Services Research

Background:

  • Chronic hepatitis B (HBV) infection presents challenges in treatment access and adherence.
  • Sociocultural, healthcare system, and economic factors impede effective HBV management.
  • Patient values and preferences are crucial for aligning evidence-based policies with universal treatment approaches.

Purpose of the Study:

  • To explore patient values and preferences in chronic hepatitis B (HBV) care.
  • To identify barriers and facilitators to HBV treatment uptake and adherence in South Asia.
  • To inform policy development for improved HBV management.

Main Methods:

  • Mixed-methods study combining cross-sectional surveys and qualitative data (focus groups, interviews) in five South Asian countries.
  • Thematic analysis of qualitative data to understand patient perceptions and experiences.
  • Quantitative analysis of demographic, socioeconomic, and clinical factors influencing HBV treatment.

Main Results:

  • Qualitative themes: psychological burden of HBV, desire to protect family, importance of guidance and social support.
  • Higher education (OR: 2.0), family support (OR: 1.9), and urban residence (OR: 1.7) predicted HBV treatment uptake.
  • Significant knowledge gaps identified: only 20.5% recognized HBV as chronic; need for family counseling highlighted.

Conclusions:

  • Patient values and lived experiences must be integrated into HBV care models and policies.
  • Simplified care, enhanced counseling, family engagement, and affordability can overcome treatment barriers.
  • Addressing knowledge gaps and providing social support are vital for HBV treatment adherence.
Abstract

Keywords:
care pathwayshealth seeking behaviorhepatitis Bquality of lifestigma

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