[Cervical cancer metastasis to the lumbosacral spinal root: a case report]
Chizuko Sugita1, Yoshitsugu Nakamura1, Yukiyo Yoshimoto1
1Division of Neurology, Department of Internal Medicine IV, Osaka Medical and Pharmaceutical University Faculty of Medicine.
Abstract:
A 67-year-old woman underwent total hysterectomy for cervical cancer followed by chemotherapy, achieving partial remission. Post-treatment, lymph node metastases to the left obturator region remained decreased in size compared with pre-treatment. Nine months prior to the last chemotherapy, she developed abnormal sensations and muscle weakness in her left lower limb. Nerve conduction studies revealed axonal damage in the left tibial, peroneal, and sural nerves. Pelvic CT and lumbar MRI showed continuous contrast enhancement and enlargement of the left L5, S1, and S2 nerve roots originating from the left lumbosacral plexus. We considered this to be metastasis from the lumbosacral plexus near the lymph node metastasis site of cervical cancer to the lumbosacral nerve roots. When multiple peripheral nerves in the lumbosacral region are involved in patients with cervical cancer, the possibility of direct tumor infiltration into the adjacent nerve plexus followed by progression along axons to the nerve roots must be considered, even when the primary tumor is controlled.

