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Updated: Aug 11, 2026

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia
Published on: December 19, 2020
Eosinophilic Granulomatosis with Polyangiitis Presenting with an Acute Hypersensitivity Pneumonitis-like CT Pattern:
Shoichiro Harada1, Yasuto Ueda1, Shino Arita1
1Department of Respiratory Medicine, Tottori Prefectural Central Hospital, Japan.
Abstract:
The patient was a man in his 20s with a history of childhood asthma who presented with fever and dyspnea. Chest CT revealed diffuse bilateral centrilobular ground-glass opacities, and a history of environmental exposure suggested acute hypersensitivity pneumonitis (HP). However, bronchoalveolar lavage revealed marked eosinophilia (75%), and a transbronchial lung biopsy demonstrated small vessel vasculitis with eosinophilic infiltration. Combined with negative anti-neutrophil cytoplasmic antibodies (ANCA), ANCA-negative eosinophilic granulomatosis with polyangiitis (EGPA) was diagnosed in this patient. Prednisolone (30 mg/day) resulted in rapid improvement, and remission was maintained for 6 months. This case shows that EGPA can mimic acute HP, underscoring the diagnostic value of bronchoscopy and histopathology when eosinophilic inflammation is present.
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