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Updated: Aug 11, 2026

A Novel Murine Model of Arteriovenous Fistula Failure: The Surgical Procedure in Detail
Published on: February 3, 2016
Development, Validation, and Evaluation of a Nurse-Led Perioperative Staged Exercise Management Program for
Yang Tang1, Mengya Wang2, Mengyao Liu1
1School of Nursing, Guangzhou University of Chinese Medicine, Guangzhou Guangdong, 510006, China, gzucm.edu.cn.
A new nurse-led exercise program improved outcomes for patients with arteriovenous fistulas (AVFs) used for hemodialysis. The program enhanced AVF maturation and blood flow, demonstrating feasibility and positive results in clinical practice.
Area of Science:
- Vascular Surgery
- Nephrology Nursing
- Clinical Exercise Physiology
Background:
- Arteriovenous fistula (AVF) is the preferred hemodialysis access, but postoperative exercise guidance and support are often lacking.
- Inconsistent recommendations and limited post-discharge support can hinder optimal AVF function.
Purpose of the Study:
- To develop, validate, and evaluate a nurse-led perioperative staged exercise management program for AVF creation.
- To improve postoperative recovery and AVF maturation through structured exercise interventions.
Main Methods:
- A sequential multiphase study involving evidence review, expert consultation, pilot testing, and a prospective controlled evaluation.
- Adults undergoing radiocephalic AVF creation received either usual care or the intervention program (staged exercise, inpatient instruction, discharge confirmation, digital reminders, follow-up).
- Ultrasound, maturation, and process indicators were assessed; TREND guidelines were followed for reporting.
Main Results:
- The intervention group showed significantly higher brachial artery blood flow and diameter, and radial artery diameter at 8 weeks.
- AVF maturation rates were higher at 8 weeks (95.1% vs. 75.6%) and 12 weeks (100.0% vs. 82.9%) in the intervention group.
- The program demonstrated high adherence, feasibility, and no serious exercise-related adverse events.
Conclusions:
- The nurse-led perioperative staged exercise program is feasible and associated with improved ultrasound and maturation outcomes post-AVF creation.
- High-quality, continuous nursing management is crucial for patient recovery and AVF care, extending beyond one-time education.
- Further multicenter studies are recommended to confirm generalizability and long-term benefits.
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