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DIPLOMA Approach for Standardized Pathology Assessment of Distal Pancreatectomy Specimens
Published on: February 1, 2020
Patient-Reported Outcome Measures Following Pancreatectomy for Pancreatic Cancer: A Scoping Review
Patrick Reardon1,2, Robert Revere2, Simon Coubard2
1Department of Surgery, Western Health, Melbourne, Victoria, Australia.
ANZ Journal of Surgery
|August 10, 2026
Summary
Patient-reported outcome measures (PROMs) are vital for assessing quality of life after pancreatic ductal adenocarcinoma (PDAC) surgery. Future research should focus on developing concise, disease-specific PROMs for clinical use.
Area of Science:
- Oncology
- Surgical Outcomes
- Health Services Research
Background:
- Patient-reported outcome measures (PROMs) are crucial for evaluating quality of life (QoL) in patients undergoing pancreatectomy for pancreatic ductal adenocarcinoma (PDAC).
- Synthesizing evidence on PROMs used in this patient population is essential for guiding future research and improving clinical practice.
Purpose of the Study:
- To conduct a scoping review of PROMs utilized in patients following pancreatectomy for PDAC.
- To identify commonly used PROMs and assess their suitability for measuring QoL in this specific oncological context.
Main Methods:
- A comprehensive literature search was performed across major databases (PubMed, Embase, Medline, Cochrane Library) from 2014 onwards.
- Studies reporting patient-reported outcomes in adult patients post-pancreatectomy for PDAC were included, with screening by two independent reviewers.
- Methodological characteristics of included studies were summarized to contextualize findings.
Main Results:
- Twenty-four studies met the inclusion criteria, encompassing RCTs and cohort studies.
- The EORTC QLQ-C30 and QLQ-PAN26 were the most frequently used QoL instruments.
- Generic tools offered broad assessment but lacked specificity, while PDAC-specific tools varied in robustness; fatigue and psychological burden were common concerns. Barriers included time constraints and lack of standardization.
Conclusions:
- PROMs are indispensable for quantifying QoL post-pancreatectomy for PDAC.
- There is a need for abridged, disease-specific PROMs that are concise and compatible with routine clinical practice to enhance patient care and research.
