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A Novel Pediatric-Inclusive Biocontainment Transport Model: Evaluation of the US Portable Biocontainment Unit during
Tress Goodwin1,2, Casey Walther3, Tschuna Patterson3
1The George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
Insights
Pediatric high-consequence infectious disease (HCID) transport requires specialized planning. This study highlights the need for pediatric-specific communication, resources, and caregiver support in biocontainment units.
Area of Science:
- Emergency Medicine
- Infectious Disease
- Pediatrics
Background:
- National biocontainment transport systems, historically adult-focused, lack pediatric-specific guidance.
- Pediatric patients have unique developmental, psychosocial, and clinical needs during transport.
- Limited operational experience exists for pediatric high-consequence infectious disease (HCID) transport.
Purpose of the Study:
- To describe pediatric observations from the first deployment of the Portable Biocontainment Unit (PBCU).
- To identify considerations for pediatric-inclusive HCID transport.
- To inform improvements in national biocontainment transport systems.
Main Methods:
- Qualitative, observational evaluation during a national full-scale exercise.
- Data collection via interviews with pediatric actors/caregivers and evaluator observations.
- Multi-disciplinary debriefings to analyze simulated pediatric biocontainment transport scenarios.
Main Results:
- Pediatric transport necessitates advance planning for distinct developmental, psychosocial, and physiological needs.
- Pediatric participants experienced anxiety due to environmental factors (noise, PPE) and caregiver separation.
- Effective communication strategies and pediatric-specific clinical resources (medication guides) are crucial.
Conclusions:
- The inaugural PBCU deployment with pediatric participants identified key operational and psychosocial considerations.
- Integrating pediatric-specific planning, communication, and resources is vital for biocontainment transport.
- Findings can inform international pediatric HCID transport planning.
Introduction:
Pediatric patients present distinct developmental, psychosocial, and clinical challenges during high-consequence infectious disease (HCID) transport. Despite these differences, national biocontainment transport systems have historically been designed around adult patients, resulting in limited pediatric-specific guidance and operational experience.
Objective:
The aim of this study was to describe pediatric-specific observations from the inaugural deployment of the US Department of Health and Human Services' (HHS) Portable Biocontainment Unit (PBCU) during a national full-scale exercise and to identify considerations relevant to pediatric-inclusive HCID transport.
Methods:
A qualitative, observational evaluation was conducted during the 2025 Tranquil Passport Full-Scale Exercise. Data sources included structured interviews with pediatric actors and caregivers, evaluator observations, and facilitated multi-disciplinary debriefings. Pediatric participants simulated biocontainment transport scenarios within the PBCU across multiple sites and phases of care.
Results:
Pediatric transport within the PBCU required advance planning to address developmental, psychosocial, and physiologic needs distinct from adult care. Pediatric participants frequently described confusion or anxiety related to noise, vibration, movement, and the appearance of personnel in personal protective equipment (PPE). Communication challenges associated with masked voices were reported. Caregiver separation due to infection-control requirements was consistently described as stressful. Clinical teams identified benefits of pediatric-specific medication dosing guides and essential medication sets within the confined biocontainment environment.
Conclusions:
This inaugural deployment of the PBCU with pediatric participants identified key operational and psychosocial considerations relevant to pediatric-inclusive HCID transport. Findings supported the need for deliberate integration of pediatric-specific planning, communication strategies, and resources within biocontainment transport systems. These observations may also inform pediatric HCID transport planning in international settings where similar challenges are encountered.
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