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Colour-Guided Surgery: A Conceptual Framework for Multimodal Intraoperative Visualisation-A Narrative Review
Takashi Nonaka1,2,3, Shintaro Hashimoto1, Tetsuro Tominaga1
1Department of Surgery, Colorectal Surgery, Nagasaki University Hospital, Nagasaki, Japan.
Background:
Intraoperative imaging has evolved beyond white-light visualisation to include fluorescence imaging, colour enhancement, artificial intelligence (AI), and molecular-targeted imaging. However, these modalities are typically used independently.
Methods:
This narrative review synthesises current multimodal intraoperative imaging and presents representative clinical images and conceptual illustrations to demonstrate complementary visual information.
Results:
White-light imaging provides anatomical context; colour enhancement improves tissue contrast; fluorescence imaging adds functional information; AI supports real-time recognition; and molecular imaging enables biologically specific visualisation. These modalities collectively form layered visual information that enhances intraoperative understanding.
Conclusions:
Colour-guided surgery is proposed as a conceptual framework integrating multimodal imaging into a unified intraoperative guidance system and may provide a conceptual basis for future evaluation of multimodal intraoperative guidance in robotic and minimally invasive surgery.
