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Visible-light-enabled multicomponent synthesis of selenotetrazoles and selenocarbamates
Changjiang Wu1, Xin Li1, Dongfang Wu1
1Organoselenium Synthesis and Function Laboratory, School of Pharmacy, Nantong University, Nantong 226019, People's Republic of China. gqliu@ntu.edu.cn.
Abstract:
A visible-light-driven three-component reaction of isocyanides, diselenides and trimethylsilyl azide (TMSN3) was carried out to synthesize selenotetrazoles under mild conditions. When the solvent system and additives were adjusted, this reaction also efficiently afforded selenocarbamates. The protocol features broad substrate scope and excellent functional-group tolerance, and a plausible reaction mechanism is proposed.
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