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Effect of Tranexamic Acid on Visualization Clarity and Bleeding in Shoulder Arthroscopy: A Randomized Controlled
Y Akalin1, F Türkmensoy1, F Yesilbursali1
1Department of Orthopedics and Traumatology, Bursa Yuksek Ihtisas Training and Research Hospital, Mimar Sinan, Polis Okulu Karşısı, Emniyet Cd., Yıldırım, Bursa, Turkey.
Nigerian Journal of Clinical Practice
|August 10, 2026
Summary
Tranexamic acid (TXA) improves visualization during shoulder arthroscopy by reducing bleeding. Intravenous TXA offers superior benefits over local application and placebo for better surgical outcomes.
Area of Science:
- Orthopedic Surgery
- Minimally Invasive Procedures
- Surgical Hemostasis
Background:
- Shoulder arthroscopy is a common procedure where bleeding impacts visualization and outcomes.
- Hemarthrosis post-surgery can negatively affect patient recovery.
Purpose of the Study:
- To evaluate the efficacy of tranexamic acid (TXA) in improving intraoperative visualization during shoulder arthroscopy.
- To determine if TXA reduces bleeding and its impact on surgical clarity.
Main Methods:
- A randomized controlled trial involving 120 patients divided into intravenous TXA, local TXA, and placebo groups.
- Intraoperative visualization was graded, and blood loss (hemoglobin levels) was measured.
- Postoperative shoulder function scores (ASES, Constant, DASH) were assessed.
Main Results:
- TXA significantly improved visualization compared to placebo, with intravenous administration showing superior results.
- Intravenous TXA led to the lowest intraoperative blood loss and hemoglobin reduction.
- All groups demonstrated significant improvements in postoperative shoulder function scores.
Conclusions:
- TXA effectively reduces intraoperative and postoperative bleeding in shoulder arthroscopy.
- Intravenous administration of TXA is more effective than local application for enhancing visualization and minimizing blood loss.
