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Interventional Tricuspid Valve Replacement: A Structured Sequence of Procedures
Sven Möbius-Winkler1, Ali Hamadanchi2, Aurel Maloku2
1Dept. of Internal Medicine I, Cardiology, Angiology, Intensive Medical Care, University Hospital Jena; sven.moebius-winkler@med.uni-jena.de.
Journal of Visualized Experiments : Jove
|August 10, 2026
Summary
The EVOQUE valve system offers a new percutaneous solution for severe tricuspid regurgitation (TR). This minimally invasive procedure effectively replaces the tricuspid valve, resolving TR in most patients.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Biomaterials Science
Background:
- Severe tricuspid regurgitation (TR) significantly impacts patient quality of life and prognosis.
- Current treatment options for TR are limited, especially for patients unsuitable for surgery.
- The EVOQUE valve system represents a novel approach to tricuspid valve replacement.
Purpose of the Study:
- To present a detailed protocol for the percutaneous implantation of the EVOQUE tricuspid bioprosthesis.
- To outline the procedural steps, including valve delivery, positioning, and deployment.
- To highlight the role of transesophageal echocardiography (TEE) in guiding the procedure.
Main Methods:
- Percutaneous implantation via the femoral vein using a dedicated delivery system.
- The EVOQUE valve features a Nitinol frame and a bovine pericardium leaflet.
- The procedure is performed under general anesthesia with continuous TEE guidance.
Main Results:
- The EVOQUE valve system is the first approved device for percutaneous tricuspid valve replacement.
- The implantation procedure is demonstrated to be safe and efficient.
- Most patients experience complete resolution of tricuspid regurgitation post-procedure.
Conclusions:
- Percutaneous tricuspid valve replacement with the EVOQUE system is a viable option for symptomatic severe TR.
- The minimally invasive approach offers a safe and effective alternative to traditional surgery.
- This technique shows promise in improving outcomes for patients with TR.
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