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Generating a Fractal Microstructure of Laminin-111 to Signal to Cells
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Receptor specificity and translational considerations for laminin-mimetic Caf1 scaffolds: reply from authors

Yuanjinze Nie1, Nick J Reynolds1,2

  • 1Translational and Clinical Research Institute (Dermatology), Medical School, Newcastle University, Newcastle upon Tyne, UK.

The British Journal of Dermatology
|August 10, 2026
PubMed
Abstract

No abstract available in PubMed .

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Laminins are the Adhesive Proteins of Basal Lamina

Laminins are heterotrimeric proteins with high molecular mass found in the extracellular matrix. Each laminin molecule is composed of three chains, viz. alpha, beta, and gamma, coded by five, four, and three paralogous genes, respectively. Laminins are categories based on the compositions of the three chains.
In humans, the five forms of alpha chains are LAMA 1, LAMA 2, LAMA 3, LAMA 4, and LAMA 5. The four forms of beta chains are LAMB 1, LAMB 2, LAMB 3, and LAMB 4. The three forms of gamma...

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