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Citrate Burden: The Missing Variable in Whole Blood Versus Component Therapy Comparisons

Min Uk Jang1, Kenichi A Tanaka1, Kenneth E Stewart2

  • 1Department of Anesthesiology University of Oklahoma Health Sciences Center Oklahoma City, Oklahoma.

Anesthesia and Analgesia
|August 10, 2026
PubMed
Summary

No abstract available in PubMed .

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When drugs enter systemic circulation, they interact with various components of the blood, including proteins such as human serum albumin (HSA), α1-acid glycoprotein (AAG), lipoproteins, globulins, and red blood cells (RBCs).
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