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Updated: Aug 12, 2026

Visualization of Amyloid β Deposits in the Human Brain with Matrix-assisted Laser Desorption/Ionization Imaging Mass Spectrometry
09:31

Visualization of Amyloid β Deposits in the Human Brain with Matrix-assisted Laser Desorption/Ionization Imaging Mass Spectrometry

Published on: March 7, 2019

Brain-seeded 42-residue Amyloid-β Fibrils That Resemble Fibrils Directly Extracted From Alzheimer's Disease Brain

Kent R Thurber1, Myungwoon Lee2, Robert Tycko1

  • 1Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892-0520, United States.

Journal of Molecular Biology
|August 10, 2026
PubMed
Abstract

Keywords:
Alzheimer’s diseaseamyloid-βcryogenic electron microscopyfibril structurepolymorphism

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