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Myeloid Cell Isolation from Mouse Skin and Draining Lymph Node Following Intradermal Immunization with Live Attenuated Plasmodium Sporozoites
Published on: May 18, 2016
Evidence for the multistage malaria vaccine gamble
Chester J Joyner1, Amadis R Vivas1, Wayne T Cheng1
1Center for Vaccines and Immunology, College of Veterinary Medicine, University of Georgia, Athens, GA, USA; Center for Tropical and Emerging Global Diseases, Office of Research, University of Georgia, Athens, GA, USA; Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, GA, USA.
Abstract:
New vaccines to reduce disease and mortality caused by Plasmodium falciparum malaria are urgently needed. Most vaccines target a single life-cycle stage and confer modest protection. Kirtley et al. test whether multistage immunity can improve protection and provide some of the first evidence that 'multistage' vaccines should be pursued.

