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A Fast and Quantitative Method for Post-translational Modification and Variant Enabled Mapping of Peptides to Genomes
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The proteome comes of age, but precision oncology needs functional maps

Emanuel Petricoin1, Thomas Conrads2,3, Lance Liotta4

  • 1Center for Applied Proteomics and Molecular Medicine, George Mason University, Manassas, VA, USA. epetrico@gmu.edu.

Nature Reviews. Clinical Oncology
|August 10, 2026
PubMed
Abstract

No abstract available in PubMed .

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Proteomics01:33

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term proteomics...

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