Related Experiment Video
Updated: Aug 12, 2026

09:57
A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit
Published on: July 13, 2019
Factors Associated With Non-First-Attempt Success in Peripheral Intravenous Cannulation by an Intravenous Therapy
Mei-Jung Wu1,2, Ming-Chin Lin3,4,5, Chi-Ming Yang2
1Research Center in Nursing Clinical Practice, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan.
Journal of Clinical Nursing
|August 11, 2026
Summary
Difficult peripheral intravenous cannulation is common. Key factors for first-attempt success include nurse experience, catheter size, and insertion site, with patient mobility being a novel indicator.
Area of Science:
- Medical Devices
- Nursing
- Clinical Practice
Background:
- Peripheral intravenous cannulation (PIVC) failure is frequent in hospitalized patients.
- Factors influencing PIVC success by dedicated teams on general wards are not well understood.
Purpose of the Study:
- Identify patient, operator, and procedural factors linked to PIVC non-first-attempt success.
- Focus on PIVC performed by intravenous therapy teams in general medical and surgical settings.
Main Methods:
- Prospective observational study analyzing PIVC events over one year.
- Generalized linear mixed model used to determine factors associated with non-first-attempt success (≥2 attempts).
Main Results:
- Approximately 20% of PIVC events required multiple attempts.
- Lower nurse experience, reduced patient mobility, smaller catheter gauge, difficult access replacement, and lower-limb/trunk sites were associated with failure.
- Patient age, sex, comorbidities, and BMI were not significant factors.
Conclusions:
- Nurse experience, catheter gauge, and insertion site are modifiable factors influencing PIVC success.
- Patient mobility is a novel, easily assessed indicator for PIVC risk.
- Findings can guide training, protocols, and bedside screening to minimize PIVC failures.

