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Updated: Aug 12, 2026

05:08
A Practical Guide to Phage- and Robotics-Assisted Near-Continuous Evolution
Published on: January 12, 2024
Building a future for phage-based technologies-a thought leadership approach to accelerating progress in the UK
Francesca E Hodges1, Darren L Smith2
1Innovate UK Business Connect, Business Design Centre, 52 Upper Street, Islington, London N1 0QH, United Kingdom.
Summary
Antimicrobial resistance is a growing global threat. Bacteriophages offer a promising alternative, and the UK's Phage Innovation Network (PIN) is accelerating their development and application.
Area of Science:
- Microbiology
- Biotechnology
- Public Health
Background:
- Antimicrobial resistance (AMR) poses a significant threat to human, animal, and environmental health.
- Bacteriophages (phages) are viruses that infect bacteria, presenting a viable alternative to conventional antimicrobials.
- The UK possesses substantial expertise and infrastructure conducive to phage technology development.
Purpose of the Study:
- To establish the Phage Innovation Network (PIN) to advance phage-based technologies in the UK.
- To address key challenges hindering the development and deployment of phage therapies.
- To foster collaboration within the phage community and with wider stakeholders.
Main Methods:
- Comprehensive consultation with the phage community and stakeholders.
- Identification of critical issues impeding phage technology progress.
- Implementation of targeted activities to overcome identified barriers.
Main Results:
- Increased engagement across the phage sector.
- Development of practical solutions for phage technology advancement.
- Demonstrated effectiveness of a thought leadership approach in driving progress.
Conclusions:
- The PIN has successfully catalyzed progress in the UK phage sector.
- Collaborative efforts and strategic interventions are crucial for overcoming AMR.
- Phage-based technologies represent a vital component of future antimicrobial strategies.
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