The Relationship Between Neonatal and Maternal Factors and the Timing of Primary Tooth Eruption in Preterm Infants:

Ali Karimi Farani1, Mohammadamin Parsaei2, Ava Taghizadeh3

  • 1School of Dentistry Tehran University of Medical Sciences Tehran Iran.

Health Science Reports
|August 11, 2026
PubMed

Insights

Preterm birth is linked to delayed primary tooth eruption. Breastfeeding and birth factors like gestational age influence eruption timing in premature infants.

Area of Science:

  • Neonatal Health
  • Pediatric Dentistry
  • Developmental Biology

Background:

  • Preterm birth is a known risk factor for delayed primary tooth eruption.
  • Limited data exists on specific neonatal and maternal factors influencing this delay in premature infants.

Purpose of the Study:

  • To investigate neonatal and maternal factors affecting the timing of the first primary tooth eruption in preterm infants.
  • To identify predictors for both chronological and corrected age of tooth eruption.

Main Methods:

  • Retrospective-prospective cohort study of 145 preterm neonates.
  • Data collection included maternal comorbidities, birth details, and neonatal status.
  • Weekly follow-up assessed tooth eruption and feeding; linear regression analyzed predictors.

Main Results:

  • Higher gestational age, male sex, and larger head circumference predicted earlier chronological eruption.
  • Lower gestational age, birthweight, and head circumference predicted earlier corrected-age eruption.
  • Exclusive breastfeeding correlated with earlier chronological eruption.

Conclusions:

  • Feeding status and anthropometric indices at birth are independent predictors of tooth eruption timing.
  • Exclusive breastfeeding is associated with earlier chronological tooth eruption.
  • Earlier corrected-age eruption in more premature infants may indicate compensatory growth.
Abstract

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