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Association Between Nutritional Risk and Physical Function Improvements in Cardiovascular Disease Patients With
Yuji Oda1,2, Kazufumi Kitagaki3, Hirokatsu Unzai1
1Department of Rehabilitation, Suita Tokushukai Hospital Osaka Japan.
Circulation Reports
|August 11, 2026
Summary
Nutritional risk in cardiovascular patients did not significantly impact physical function recovery in the primary analysis. However, sensitivity analyses indicated a potential link between malnutrition and impaired physical function improvement.
Area of Science:
- Cardiology
- Geriatrics
- Nutritional Science
Background:
- Investigated the link between nutritional risk and physical function in cardiovascular disease patients, especially heart failure, during hospitalization.
- Focused on community-based care wards, a critical setting for patient recovery and rehabilitation.
Purpose of the Study:
- To determine if nutritional risk, assessed by Mini Nutritional Assessment-Short Form (MNA-SF), predicts lack of physical function improvement in hospitalized cardiovascular patients.
- To analyze the association between malnutrition and physical function outcomes using robust statistical methods.
Main Methods:
- Retrospective analysis of 84 cardiovascular patients undergoing cardiac rehabilitation.
- Classified patients into malnourished (MNA-SF ≤7) and non-malnourished (MNA-SF ≥8) groups.
- Assessed physical function using Short Physical Performance Battery (SPPB) and employed propensity score-adjusted modified Poisson regression.
Main Results:
- 25% of patients showed no improvement in physical function (primary outcome).
- Malnutrition was not significantly associated with no physical function improvement in the primary analysis (aRR 1.16; P=0.71).
- Sensitivity analysis revealed a significant association between malnutrition and no physical function improvement (aRR 2.3; P<0.001).
Conclusions:
- Nutritional risk did not show a significant association with lack of physical function improvement in the primary analysis.
- Sensitivity analyses, using an alternative definition for poor physical function, indicated a significant association between malnutrition and impaired recovery.
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