Related Experiment Video
Updated: Aug 12, 2026
10:42
A Postoperative Evaluation Guideline for Computer-Assisted Reconstruction of the Mandible
Published on: January 28, 2020
Early Postoperative Cognitive Performance After Total Arch Replacement: A Prospective Observational Study
Kyosuke Takahashi1, Misa Kajitani2, Wataru Takayama3
1Department of Anesthesiology, Institute of Science Tokyo Hospital, Tokyo, Japan.
Anesthesiology Research and Practice
|August 11, 2026
Summary
Cognitive recovery after total arch replacement gradually improves post-surgery but remains incomplete for many patients by day 7. Serial cognitive assessments are crucial for complex aortic surgery patients.
Area of Science:
- Cardiovascular Surgery
- Neuroscience
- Geriatric Medicine
Background:
- Cognitive trajectories post-total arch replacement (TAR) are not well understood.
- Early postoperative cognitive function is critical for patient outcomes.
Purpose of the Study:
- To evaluate serial postoperative cognitive recovery patterns after TAR.
- To characterize cognitive performance during the first postoperative week.
Main Methods:
- Adult patients undergoing elective TAR were enrolled.
- The Postoperative Quality of Recovery Scale (PostopQRS) assessed recovery at multiple time points.
- Cognitive recovery was analyzed using the revised PostopQRS algorithm.
Main Results:
- Cognitive recovery was observed in 56.1% at 3 hours, increasing to 75.6% by postoperative Day 3.
- While other recovery domains improved, nociceptive recovery remained incomplete, driven by pain.
- Cognitive recovery was incomplete in 26.8% of patients by postoperative Day 7.
Conclusions:
- Postoperative cognitive recovery after TAR is gradual but incomplete in a significant portion of patients.
- Findings underscore the heterogeneous nature of cognitive recovery.
- Serial cognitive assessment is vital after complex aortic surgery.