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Published on: February 9, 2011

Infusion-Site MSSA as the Source of Confirmed Toxic Shock Syndrome in a 9-Year-Old on Automated Insulin Delivery

Fabio Rotondo1,2, Sofia Siena1, Carmela De Meco1

  • 1Department of Pediatrics, IRCCS "Casa Sollievo Della Sofferenza", San Giovanni Rotondo, Italy, operapadrepio.it.

Case Reports in Pediatrics
|August 11, 2026
PubMed

Insights

A rare Staphylococcal toxic shock syndrome (TSS) case in a girl using automated insulin delivery highlights infusion sites as infection sources. The study supports continuing this diabetes technology during critical illness.

Area of Science:

  • Pediatric critical care medicine
  • Infectious diseases
  • Endocrinology

Background:

  • Staphylococcal toxic shock syndrome (TSS) is a rare, toxin-mediated illness.
  • Automated insulin delivery systems are crucial for managing type 1 diabetes.
  • Infusion site infections can lead to severe complications.

Purpose of the Study:

  • To report a case of TSS in a pediatric patient on automated insulin delivery.
  • To emphasize the role of infusion sites as potential foci for sepsis.
  • To support the continued use of automated insulin delivery in critically ill patients.

Main Methods:

  • Case report of a 9-year-old girl.
  • Clinical presentation: shock, multiorgan dysfunction, rash, gastrointestinal symptoms.
  • Microbiological analysis: methicillin-susceptible Staphylococcus aureus (MSSA) from infusion site.

Main Results:

  • The patient met the CDC criteria for TSS.
  • The infected infusion site was identified as the source of infection.
  • Successful management while maintaining automated insulin delivery.

Conclusions:

  • Infusion sites for automated insulin delivery can serve as critical foci for sepsis.
  • Continuation of automated insulin delivery is supported during critical illness in selected cases.
  • Early recognition and management of TSS are essential.
Keywords:
AIDTSSautomated insulin deliverydiabetes mellituspediatric infectiontoxic shock syndrome

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