Related Experiment Video
Updated: Aug 12, 2026

08:58
Atomic Force Microscopy Cantilever-Based Nanoindentation: Mechanical Property Measurements at the Nanoscale in Air and Fluid
Published on: December 2, 2022
Unveiling Van Der Waals Forces and Associated Hamaker Constants Across the Nanomaterial Landscape With Advanced
Amir Farokh Payam1, Horacio V Guzman2, Alexandre Tkatchenko3
1Nanotechnology and Integrated Bioengineering Centre, School of Engineering, Ulster University, Newtownabbey, UK.
Small Methods
|August 11, 2026
Summary
Atomic force microscopy (AFM) precisely quantifies nanoscale Van der Waals (vdW) forces and Hamaker constants. This review highlights AFM
Area of Science:
- Physics
- Materials Science
- Biophysics
Background:
- Van der Waals (vdW) forces and Hamaker constants are crucial for nanoscale phenomena.
- Precise quantification of vdW interactions is challenging due to limitations in conventional methods.
- Atomic force microscopy (AFM) offers high-resolution, nondestructive measurement capabilities.
Purpose of the Study:
- To review the physics of vdW interactions.
- To discuss advancements in AFM methodologies for vdW force quantification.
- To explore applications and future prospects of AFM in vdW force detection.
Main Methods:
- Review of vdW interaction physics.
- Analysis of advanced AFM techniques for nanoscale force measurements.
- Integration of AFM with quantum mechanical frameworks.
Main Results:
- AFM overcomes spatial resolution limitations of conventional methods.
- AFM enables high-resolution, nondestructive measurement of vdW forces and Hamaker constants.
- AFM applications demonstrated in 2D materials and biological systems.
Conclusions:
- AFM is a powerful tool for quantifying vdW forces at the nanoscale.
- AFM facilitates understanding of critical interactions in materials and biological systems.
- Emerging AFM integrations promise unprecedented accuracy for novel applications.
Related Concept Videos
Atomic Force Microscopy
Atomic force microscopy (AFM) is a type of scanning probe microscopy that can analyze topographic details of various specimens like ceramics, glass, polymers, and biological samples. AFM offers over 1000 times more resolution than the optical imaging system. Images generated from AFM are three-dimensional surface profiles, offering an advantage over the flat, two-dimensional images from other imaging techniques.
The AFM Probe
The probe is regarded as the heart of any AFM setup and comprises the...
The AFM Probe
The probe is regarded as the heart of any AFM setup and comprises the...
Van der Waals Interactions
Atoms and molecules interact with each other through intermolecular forces. These electrostatic forces arise from attractive or repulsive interactions between particles with permanent, partial, or temporary charges. The intermolecular forces between neutral atoms and molecules are ion–dipole, dipole–dipole, and dispersion forces, collectively known as van der Waals forces.Polar molecules have a partial positive charge on one end and a partial negative charge on the other end of the molecule,...
