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Low-dose atropine-related esotropia in a myopic child: a case report

Athanasia Sandali1, Michail Angelos Gkikas1, Anna Nikolaidou2

  • 1Programme of Postgraduate Studies, MSc "Ocular Surgery", School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece.

Strabismus
|August 11, 2026
PubMed

Insights

Low-dose atropine (LDA) eye drops for myopia control in children may rarely cause esotropia, a form of strabismus. This case highlights the importance of monitoring for potential side effects during LDA treatment.

Area of Science:

  • Ophthalmology
  • Pediatric Ophthalmology
  • Myopia Control

Background:

  • Acute-onset strabismus in highly myopic children requires a broad differential diagnosis.
  • Prolonged near focus and screen time are associated with myopia progression.
  • Low-dose atropine (LDA) is increasingly used for myopia control.

Purpose of the Study:

  • To report a rare case of esotropia developing during LDA treatment for myopia.
  • To highlight potential side effects of LDA in pediatric myopia management.

Main Methods:

  • A case report of a four-year-old male with high myopia and prolonged near focus.
  • Treatment with 0.05% atropine eye drops for progressive myopia.
  • Observation of strabismus development and management.

Main Results:

  • The patient developed esophoria, which progressed to esotropia within one month of starting LDA.
  • LDA treatment was discontinued due to myopia progression.
  • The patient ultimately required strabismus surgery for persistent esotropia.

Conclusions:

  • LDA is effective for myopia control but may have rare side effects like esotropia.
  • This case is among the first to document esophoria converting to esotropia in a pediatric patient treated with LDA.
  • Vigilant monitoring for strabismus is crucial during LDA therapy for myopia.
Abstract

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