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Phage Therapy Application to Counteract Pseudomonas aeruginosa Infection in Cystic Fibrosis Zebrafish Embryos
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First-in-Human Adjunctive Bacteriophage Therapy for Malakoplakia

Saima Aslam1, Aleah Brubaker2, Mita Shah3

  • 1Division of Infectious Diseases and Global Public Health, University of California San Diego, La Jolla, California, USA.

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
|August 11, 2026
PubMed
Summary

This study shows bacteriophage therapy can successfully treat Escherichia coli malakoplakia in kidney transplant patients. The novel CRISPR-enhanced phage SNIPR001, combined with other treatments, led to lesion resolution and disease regression without side effects.

Keywords:
kidney transplantmalakoplakiaphage therapy

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