Related Experiment Video
Updated: Aug 12, 2026

In Silico Clinical Trials for Cardiovascular Disease
Published on: May 27, 2022
Developmental Systems Cardiology II: Implementing a Lifespan Model for Clinical Practice
Colin J McMahon1,2, Jeffrey Kim3, Mark Lewin4
1Department of Pediatric Cardiology, Children's Health Ireland, Dublin 12, Crumlin, Ireland. cmcmahon992004@yahoo.com.
Insights
Survival rates for children with congenital heart disease (CHD) have improved. A new framework, Developmental Systems Cardiology, integrates lifelong care, addressing neurodevelopmental and psychosocial needs for better adaptation.
Area of Science:
- Cardiology
- Developmental Pediatrics
- Health Systems Science
Background:
- Improved survival in congenital heart disease (CHD) necessitates lifelong care.
- Evolving congenital cardiology requires addressing neurodevelopmental and psychosocial challenges.
- Existing care models lack practical implementation guidance for integrated, lifelong support.
Purpose of the Study:
- To present a practical framework for integrating Developmental Systems Cardiology into pediatric and adult congenital cardiology programs.
- To guide the implementation of multidisciplinary structures and longitudinal care pathways.
- To support adaptation and improve outcomes across the lifespan for individuals with CHD.
Main Methods:
- Development of a practical implementation framework for Developmental Systems Cardiology.
- Integration of multidisciplinary structures, longitudinal care pathways, and neurodevelopmental surveillance.
- Focus on organizational redesign, transition medicine, and quality frameworks for real-world application.
Main Results:
- The framework outlines practical approaches from fetal diagnosis to adult care.
- Key components include integrated neurodevelopmental follow-up, family-centered communication, and transition pathways.
- Emphasis on overcoming challenges in real-world pediatric cardiac systems, such as resource variation and fragmentation.
Conclusions:
- Developmental Systems Cardiology offers an integrated, longitudinal system beyond episodic care.
- The framework supports neurodevelopment, family adaptation, and successful transition to adulthood.
- Sustainable, multidisciplinary systems are crucial for future progress in congenital cardiology.
Abstract:
Survival for children with congenital heart disease (CHD) has improved substantially because of advances in surgery, intensive care, imaging, and interventional cardiology. As congenital cardiology evolves into a lifespan discipline, healthcare systems must also address neurodevelopmental vulnerability, psychosocial adaptation, educational disruption, transition complexity, and chronic multisystem disease in adulthood. Although developmental and systems-oriented models of care are emerging, practical guidance for implementation within routine congenital cardiology programs remains limited. This article presents a practical implementation framework for integrating Developmental Systems Cardiology into pediatric and adult congenital cardiology programs through multidisciplinary structures, longitudinal care pathways, neurodevelopmental surveillance, transition medicine, organizational redesign, and measurable quality frameworks. We outline practical approaches spanning fetal diagnosis through adult congenital heart disease care. These include integrated neurodevelopmental follow-up, family-centered communication systems, multidisciplinary Fontan programs, adolescent transition pathways, psychosocial support services, and workforce structures that support longitudinal continuity. Particular emphasis is placed on implementation within real-world pediatric cardiac systems, where resource variation, workforce limitations, and institutional fragmentation frequently challenge coordinated care. Developmental Systems Cardiology moves congenital cardiology beyond isolated episodic models toward integrated longitudinal systems that support adaptation across the lifespan. The framework is intended as a practical and scalable clinical model rather than a prescriptive doctrine. Implementation will appropriately vary according to institutional resources and regional healthcare systems. Future progress in congenital cardiology will depend not only on continued improvements in survival and procedural outcomes, but also on sustainable multidisciplinary systems that support neurodevelopment, family adaptation, educational participation, psychosocial wellbeing, and successful transition into adulthood.
Related Concept Videos
Cardiomyopathy V: Interprofessional Care
Cardiomyopathy VI: Nursing Management
Cardiomyopathy II: Dilated Cardiomyopathy
Heart Failure II: Pathophysiology
Cardiomyopathy I: Introduction and Classification
Heart Failure III: Clinical Manifestations