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Sexual Dysfunction in Women with Axial Spondyloarthritis: A Narrative Review Integrating Quantitative Evidence
Gabriela Stutz F Moreira1, Hemerli de Cinque Almeida Esteves2, Lucas M Barbosa3
1Rheumatology Department, Federal Hospital of Servants of Rio de Janeiro, Rio de Janeiro, Brazil. gabrielastutz@hotmail.com.
Current Rheumatology Reports
|August 11, 2026
Summary
Sexual dysfunction is common in women with axial spondyloarthritis (axSpA). It results from inflammation, pain, and psychological factors, impacting quality of life.
Area of Science:
- Rheumatology
- Sexual Medicine
- Women's Health
Background:
- Sexual dysfunction is prevalent and impactful in women with axial spondyloarthritis (axSpA).
- Understanding the multifactorial mechanisms is crucial for improving patient care.
Purpose of the Study:
- To synthesize biological, clinical, and psychosocial factors contributing to sexual dysfunction in axSpA.
- To integrate existing literature with quantitative evidence.
Main Methods:
- Comprehensive literature review.
- Meta-analysis of quantitative data (547 women).
Main Results:
- Sexual dysfunction in axSpA is multifactorial, involving inflammation, pain, fatigue, and psychological distress.
- Lower Female Sexual Function Index scores observed in axSpA patients compared to controls.
- Arousal, lubrication, orgasm, pain, and desire are particularly affected.
Conclusions:
- Sexual dysfunction in axSpA involves a complex interplay of inflammatory, physical, psychological, and structural factors.
- A multidisciplinary approach and systematic sexual health assessment are recommended for routine care.
