Related Experiment Video

Updated: Aug 13, 2026

Murine Dermal Fibroblast Isolation by FACS
06:04

Murine Dermal Fibroblast Isolation by FACS

Published on: January 7, 2016

Periostin defines a pathological fibroblast program enriched in restrictive allograft syndrome

Yudai Miyashita1, Taisuke Kaiho1, Yuriko Yagi1

  • 1Division of Thoracic Surgery and.

JCI Insight
|August 11, 2026
PubMed

Abstract:

This study identifies POSTN-positive pathological fibroblasts as key contributors to fibrotic restrictive chronic lung allograft dysfunction after lung transplantation.

Keywords:
ImmunologyOrgan transplantationPulmonology

More Related Videos

Rapid Isolation of BMPR-IB+ Adipose-Derived Stromal Cells for Use in a Calvarial Defect Healing Model
09:07

Rapid Isolation of BMPR-IB+ Adipose-Derived Stromal Cells for Use in a Calvarial Defect Healing Model

Published on: February 24, 2017

Ultrasonic-augmented Primary Adult Fibroblast Isolation
06:51

Ultrasonic-augmented Primary Adult Fibroblast Isolation

Published on: July 29, 2019

Related Experiment Videos

Last Updated: Aug 13, 2026

Murine Dermal Fibroblast Isolation by FACS
06:04

Murine Dermal Fibroblast Isolation by FACS

Published on: January 7, 2016

Rapid Isolation of BMPR-IB+ Adipose-Derived Stromal Cells for Use in a Calvarial Defect Healing Model
09:07

Rapid Isolation of BMPR-IB+ Adipose-Derived Stromal Cells for Use in a Calvarial Defect Healing Model

Published on: February 24, 2017

Ultrasonic-augmented Primary Adult Fibroblast Isolation
06:51

Ultrasonic-augmented Primary Adult Fibroblast Isolation

Published on: July 29, 2019

Related Concept Videos

Introduction to Fibroblasts01:09

Introduction to Fibroblasts

Rudolph Virchow discovered spindle-shaped cells called fibroblasts in 1858. Inactive fibroblasts, called fibrocytes, become activated by various stimuli, such as growth factors and inflammatory cytokines. Activated fibroblasts play a crucial role in wound healing, inflammation, formation of new blood vessels, and cancer progression. Uncontrolled activation of fibroblasts results in fibrosis, the excess deposition of fibrous tissue, which can lead to scarring and affect normal organs. This...

Articles linked to this work by shared authors, journal, and citation graph.

Pathological Th2 cell activation via STAT6 pathway for pulmonary fibrosis.

American journal of respiratory cell and molecular biology·2026

Doxycycline for epistaxis in hereditary hemorrhagic telangiectasia: genotype-stratified outcomes.

Blood vessels, thrombosis & hemostasis·2026

Impact of preoperative venovenous extracorporeal membrane oxygenation bridging on postoperative acute kidney injury after lung transplantation.

Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs·2026

Mesothelioma: Pleural, Version 3.2026, NCCN Clinical Practice Guidelines In Oncology.

Journal of the National Comprehensive Cancer Network : JNCCN·2026

Phenotyping immune sensitization reveals pattern-based association with post-lung transplant complications.

JHLT open·2026

Myasthenia thymus reprograms class-switched B cells into BAFF-dependent survivors.

Science advances·2026

T-cell responses shape infant SIV reservoirs and post-intervention control following AAV9-eCD4-Ig and latency reversal.

JCI insight·2026

Loss of ADAMTS9 disrupts ciliogenesis and collagen homeostasis resulting in Nephronophthisis-like polycystic kidneys.

JCI insight·2026

Long-term reprogramming of classical monocytes with altered ontogeny mediates enhanced lung injury in sepsis survivors.

JCI insight·2026

The E3 ubiquitin ligase HECTD3 controls immune colonic inflammation by restricting Myd88 activation and signaling.

JCI insight·2026

Vorinostat for graft-versus-host disease prevention in pediatric and young adult patients with hematologic malignancies.

JCI insight·2026

SIV infection disrupts the spatial cellular and communication networks of pulmonary granulomas during SIV/MTB co-infection.

JCI insight·2026

A Jacketed Telemetry Method for Monitoring Cardiorespiratory Adaptation During Exercise in Rats.

Journal of visualized experiments : JoVE·2026

Early Prediction of Postoperative Urinary Retention After General Anesthesia Using Explainable Machine Learning.

Journal of multidisciplinary healthcare·2026

The Economics of Intraoperative Parathyroid Hormone Monitoring for Parathyroid Surgery: A Scoping Review of Cost Analyses and Economic Evaluations.

Laryngoscope investigative otolaryngology·2026

Sex-specific clinical history improves disease prediction while revealing context-dependent effects on fairness in multimorbid populations.

International journal of medical informatics·2026

Group A Streptococcal Perimyocarditis Presenting With Acute Left Ventricular Dysfunction.

JACC. Case reports·2026

Stratified Fascicular Conduction: A Cause of Predicted Interval Mismatch for Ablation of Premature Ventricular Contraction From the Left Posterior Fascicle.

JACC. Case reports·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us