Related Experiment Video
Updated: Aug 13, 2026

08:58
Enhanced Rabies Surveillance Using a Direct Rapid Immunohistochemical Test
Published on: April 30, 2019
Rabies post-exposure prophylaxis after previous immediate hypersensitivity: A case report
Murat Duyan1, Mehmet Akcimen1, Dilara Balci2
1Department of Emergency Medicine, Antalya Training and Research Hospital, Antalya, Turkey.
The American Journal of Emergency Medicine
|August 11, 2026
Summary
Rabies post-exposure prophylaxis can be safely administered to patients with a history of immediate hypersensitivity. Careful monitoring and preparedness for anaphylaxis are crucial for successful rabies prevention.
Area of Science:
- Immunology
- Infectious Diseases
- Public Health
Background:
- Rabies is a fatal viral disease preventable by post-exposure prophylaxis (PEP).
- Immediate hypersensitivity reactions to rabies vaccines can complicate PEP administration.
- Previous vaccine reactions often lead to PEP discontinuation, increasing rabies risk.
Keywords:
AnaphylaxisCat biteEmergency departmentPost-exposure prophylaxisRabiesRabies immunoglobulinVaccine allergyMore Related Videos
Related Concept Videos
Rabies
Rabies is a lethal zoonotic disease caused by a single-stranded, negative-sense RNA virus of the Lyssavirus genus, within the family Rhabdoviridae. Its primary mode of transmission to humans is through bites or saliva-contaminated scratches from infected mammals such as dogs, bats, raccoons, or foxes. Transmission can also occur if infectious saliva contacts abraded skin or intact mucous membranes, including the conjunctiva.Viral Entry and Early ReplicationOnce introduced at the bite or scratch...
Rocky Mountain Spotted Fever
Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.
Respiratory Syncytial Virus Disease
Human respiratory syncytial virus (RSV) is a widespread pathogen that primarily targets infants and young children but also poses a serious health risk to elderly and immunocompromised individuals. Belonging to the Pneumoviridae family, RSV is a negative-sense, single-stranded RNA virus within the Pneumovirus genus. Its global health burden is significant, with millions of cases annually resulting in hospitalizations and mortality, particularly in resource-limited settings. Although most...
Allergic Reactions
Overview
Chickenpox
Chickenpox is an acute, highly contagious disease caused by the varicella-zoster virus (VZV), a double-stranded DNA virus belonging to the Herpesviridae family. Its transmission occurs primarily through the inhalation of respiratory droplets or direct contact with vesicular fluid from skin lesions. The incubation period typically ranges from 10 to 21 days, during which the virus replicates and disseminates through sequential phases within the host. Although generally self-limiting in children,...

