Molecular recognition-driven fluorescence quenching based sensing of ascorbic acid using a β-cyclodextrin/graphene...

Area of Science:

• Nanomaterials Science
• Analytical Chemistry
• Food Science

Background:

• Ascorbic acid (AA) is a vital nutrient and antioxidant in food.
• Accurate detection of AA is crucial for food quality and safety.
• Existing detection methods may lack sensitivity, cost-effectiveness, or portability.

Purpose of the Study:

• To develop a sensitive and cost-effective fluorescent sensing system for ascorbic acid (AA) detection.
• To utilize a β-CD/GO nanohybrid material for enhanced sensing capabilities.
• To validate the sensor's performance in real food samples.

Main Methods:

• Synthesis of β-CD/GO nanohybrid via a hydrothermal approach.
• Characterization using XRD, FTIR, Raman, zeta potential, and particle size analysis.
• Fluorescence quenching mechanism based on host-guest interaction and photoinduced electron transfer (PET).

Main Results:

• The β-CD/GO nanohybrid demonstrated uniform surface modification.
• A linear response for AA detection was observed in the range of 2.5-40 μM.
• A low detection limit of 1.21 μM was achieved.
• Successful application in real food samples (lemon, mango, orange juices) with high recovery rates (92.3-106.4%).

Conclusions:

• The developed β-CD/GO based fluorescent sensor is effective for sensitive AA detection.
• The strategy is rapid, cost-effective, and portable, suitable for practical food safety analysis.
• This approach offers a promising tool for monitoring AA levels in various food matrices.