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Published on: March 29, 2022
Efficacy and Safety of Dual-Sided Composite Defocus Spectacles for Myopia Control in Children: A 1-Year Randomized,
Yihan Guo1, Kai Cao1, Zhaocheng Zhang2
1Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Sciences Key Laboratory, Beijing 100730, China.
Ophthalmology
|August 11, 2026
Summary
Dual-sided composite defocus (DSCD) lenses significantly reduced myopia progression in children compared to single-vision lenses. These novel spectacle lenses offer a promising, well-tolerated option for pediatric myopia control.
Area of Science:
- Ophthalmology
- Optometry
- Pediatric Eye Care
Background:
- Myopia, a common refractive error, is increasing globally in children.
- Effective myopia control strategies are crucial to prevent high myopia and associated ocular pathologies.
- Novel spectacle lens designs aim to slow axial elongation and refractive error progression.
Purpose of the Study:
- To evaluate the efficacy and safety of a novel dual-sided composite defocus (DSCD) lens for controlling myopia in children.
- To compare the myopia control effects of DSCD lenses with single-surface defocus (SSD) and single-vision spectacle (SVS) lenses.
Main Methods:
- A 1-year prospective, randomized, double-masked, three-arm clinical trial involving 225 children (aged 6-14) with myopia.
- Participants were assigned to DSCD, SSD, or SVS lenses.
- Primary outcomes included changes in axial length (AL) and spherical equivalent refraction (SER).
Main Results:
- DSCD lenses significantly reduced SER progression (-0.22 D) and axial elongation (0.19 mm) compared to SVS lenses over 12 months.
- DSCD lenses showed significantly less SER progression compared to SSD lenses, but axial elongation differences were not significant.
- DSCD lenses achieved a 73.6% reduction in SER progression and a 55.2% reduction in AL elongation relative to SVS lenses.
Conclusions:
- Dual-sided composite defocus (DSCD) lenses are effective in reducing myopia progression in children compared to single-vision spectacle (SVS) lenses.
- DSCD lenses represent a potentially valuable spectacle-based intervention for pediatric myopia management.
- The lenses were well-tolerated with no adverse events reported, indicating good safety and compliance.