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Photoselective Vaporesection of the Prostate via an End-firing Lithium Triborate Crystal Laser
Published on: May 9, 2018
Clinical factors associated with postoperative fever after bipolar TURP and GreenLight laser vaporization: a
Lei Huang1,2, Fang Guo1,2, Can Liu1,2
1Department of Urology, The Second Affiliated Hospital, Army Military Medical University, Chongqing, China.
Background:
Postoperative fever after transurethral surgery for benign prostatic hyperplasia may prompt evaluation for infection, but interpretation is complicated by catheterization, perioperative inflammation, variable microbiological sampling, and procedure-specific differences.
Methods:
We retrospectively analysed 401 patients who underwent bipolar transurethral resection of the prostate (bTURP) or GreenLight laser photoselective vaporization of the prostate (GL-PVP) from October 2019 to February 2023. The primary outcome was postoperative fever recorded during the index admission. Multivariable logistic regression was used to identify associated factors. Post hoc model checks included assessment of multicollinearity, calibration, goodness of fit, discrimination, and five-fold internal cross-validation where feasible. Available postoperative culture and antimicrobial susceptibility records were analysed descriptively.
Results:
Postoperative fever was recorded in 48 of 401 patients (11.97%), with no significant difference between bTURP and GL-PVP (11.44% vs. 12.73%; P = 0.755). In the reported multivariable model, diabetes mellitus, a positive preoperative urine culture, preoperative lower urinary tract functional testing, preoperative indwelling catheterization, and longer operative time were associated with postoperative fever. Post hoc diagnostics showed no severe multicollinearity and acceptable apparent discrimination, but the limited number of events supports cautious interpretation. The supplied postoperative culture dataset contained 24 isolate records from 22 patients; Escherichia coli (11/24) and Klebsiella pneumoniae (6/24) were most frequent. Susceptibility-test denominators varied by antimicrobial agent.
Conclusion:
Several preoperative and procedural factors were associated with postoperative fever after bTURP or GL-PVP. These associations are hypothesis-generating and should not be interpreted as causal. Because exact fever onset, complete SIRS components, culture specimen source, and standardized perioperative antibiotic protocols were unavailable, the microbiological findings should be interpreted as exploratory local surveillance data.