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Age-Related Associations Between Relative Handgrip Strength and Body Composition in Women with Obesity
Luca Cavaggioni1,2, Luisa Gilardini1, Marina Croci1
1Obesity Unit and Laboratory of Nutrition and Obesity Research, Department of Endocrine and Metabolic Diseases, IRCCS Istituto Auxologico Italiano, 20145 Milan, Italy.
Journal of Clinical Medicine
|August 13, 2026
Summary
Relative handgrip strength is linked to better body composition in women with obesity across all ages. This muscle function marker shows consistent associations, regardless of age group, offering valuable insights beyond traditional measures.
Area of Science:
- Gerontology
- Obesity Research
- Musculoskeletal Health
Background:
- Relative muscular function is a key indicator of muscle quality and health in individuals with obesity.
- Limited research exists on the age-related associations between relative handgrip strength and body composition in obese women.
- Understanding these relationships is crucial for targeted health interventions.
Purpose of the Study:
- To investigate the associations between relative handgrip strength and various body composition outcomes in a cohort of women with obesity.
- To examine whether these associations differ across different age groups.
- To explore the clinical relevance of relative handgrip strength as a marker in obesity management.
Main Methods:
- A cross-sectional study involving 419 female outpatients with obesity (aged 18-80 years).
- Body composition assessed via BMI, waist circumference (WC), fat mass percentage (FM%), and fat-free mass (FFM%).
- Relative handgrip strength (relative HST) measured alongside functional performance tests; age-stratified regressions analyzed associations.
Main Results:
- Relative HST showed significant associations with lower FM% and higher FFM% across all age groups.
- Associations with lower WC were noted in middle-aged and older women.
- No significant differences in the strength of associations between relative HST and body composition across age groups were found.
Conclusions:
- Relative handgrip strength is consistently associated with body composition in women with obesity, irrespective of age.
- These findings suggest relative HST provides valuable clinical information beyond standard anthropometric measurements.
- Further prospective research is warranted to confirm the clinical utility of relative HST in personalized obesity care.