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Published on: June 18, 2020

Circadian Blood Pressure Patterns in Adults with Moderate-to-Severe Hepatic Steatosis: A Prospective Ambulatory Blood

Nurcan Aslan1, Mustafa Comoglu1, Emra Asfuroglu Kalkan1

  • 1Department of Internal Medicine, Ankara Bilkent City Hospital, 06800 Ankara, Türkiye.

Journal of Clinical Medicine
|August 13, 2026
PubMed

Insights

Non-dipping blood pressure, a pattern where blood pressure doesn't adequately decrease at night, is common in adults with moderate-to-severe hepatic steatosis. This finding highlights potential cardiovascular risks associated with fatty liver disease.

Area of Science:

  • Cardiology
  • Hepatology
  • Hypertension Research

Background:

  • Hepatic steatosis frequently co-occurs with cardiometabolic risk factors.
  • Circadian blood pressure patterns in individuals with hepatic steatosis are not well understood.

Purpose of the Study:

  • To characterize ambulatory blood pressure patterns in adults diagnosed with moderate-to-severe hepatic steatosis.
  • To investigate the prevalence of dipper versus non-dipper blood pressure patterns in this population.

Main Methods:

  • A prospective observational study involving 137 adults with grade 2 or 3 hepatic steatosis.
  • Utilized 24-hour ambulatory blood pressure monitoring to assess blood pressure variations.
  • Classified participants as dippers or non-dippers based on nocturnal blood pressure decline.

Main Results:

  • A high prevalence of non-dipping blood pressure was observed, with 68.6% of participants classified as non-dippers.
  • The non-dipper group showed higher rates of ambulatory and nocturnal hypertension.
  • Higher 24-hour systolic blood pressure was noted in the non-dipper group compared to dippers.

Conclusions:

  • Non-dipping blood pressure is a frequent finding in adults with moderate-to-severe hepatic steatosis.
  • Ambulatory blood pressure monitoring is valuable for assessing nocturnal blood pressure patterns in this cohort.
  • The findings suggest a potential link between hepatic steatosis and abnormal circadian blood pressure regulation.

Keywords:
ambulatory blood pressure monitoringcircadian blood pressurehepatic steatosisnocturnal blood pressurenon-dipping blood pressure

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