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Experimental Validation of a Compact and Versatile Bioimpedance Measurement Platform Based on the SENSIPLUS Chip
Lorenzo Giannini1, Rita Asquini1, Alessio Buzzin2
1Department of Information Engineering, Electronics and Telecommunications, Sapienza University of Rome, 00184 Rome, Italy.
Sensors (Basel, Switzerland)
|August 13, 2026
Summary
This study validates a compact bioimpedance platform for wearable health monitoring. The device accurately measures physiological signals, showing potential for Internet of Medical Things (IoMT) applications.
Area of Science:
- Biomedical Engineering
- Wearable Technology
- Sensor Systems
Background:
- Continuous physiological monitoring is crucial for wearable and Internet of Medical Things (IoMT) devices.
- Bioimpedance analysis offers a versatile, non-invasive method for assessing tissue properties, body composition, and respiratory dynamics.
Purpose of the Study:
- To experimentally validate a compact, low-power bioimpedance measurement platform based on the SENSIPLUS chip.
- To assess the platform's metrological performance for wearable IoMT applications.
Main Methods:
- Electrical characterization using tissue-equivalent circuits and three-point calibration.
- In vivo multi-frequency bioimpedance spectroscopy (BIS) with Cole-Cole model fitting.
- Single-frequency thoracic impedance plethysmography for respiratory monitoring.
Main Results:
- The platform demonstrated a maximum resistance error below 5.7% and reactance deviation under 6 Ω.
- Cole-Cole parameters were consistent with reference values, and thoracic impedance variations strongly correlated with tidal volume (R²=0.97).
- Respiratory rate estimation errors were below 2%.
Conclusions:
- The SENSIPLUS-based bioimpedance platform achieves performance suitable for wearable IoMT applications.
- The compact system-on-chip design offers low power consumption and high accuracy for continuous physiological monitoring.
