Related Experiment Video

Updated: Aug 14, 2026

An Experimental Paradigm for the Prediction of Post-Operative Pain (PPOP)
14:56

An Experimental Paradigm for the Prediction of Post-Operative Pain (PPOP)

Published on: January 27, 2010

Multimodal strategies for alleviating postoperative pain in children: a narrative review on research progress and

Liang Du1, Xiaoqian Ma1, Hangyan Zhao1

  • 1Department of Anesthesia Surgery Center, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Children and Adolescents' Health and Diseases, Hangzhou, China.

Translational Pediatrics
|August 13, 2026
PubMed

Insights

Effective pediatric postoperative pain management uses multimodal strategies, combining non-opioid analgesics, regional techniques, and family-centered care. This approach enhances recovery and reduces opioid use in children undergoing surgery.

Area of Science:

  • Pediatric Surgery
  • Pain Management
  • Anesthesiology

Background:

  • Postoperative pain is a significant challenge in pediatric surgery, impacting recovery and outcomes.
  • Children require tailored pain management strategies due to unique developmental, physiological, and behavioral differences.
  • Effective pain control is crucial for preventing short- and long-term negative consequences.

Purpose of the Study:

  • To review recent evidence on multimodal pain management strategies for pediatric surgical patients.
  • To synthesize updated information on analgesic approaches for children undergoing surgery.
  • To highlight current trends and future directions in pediatric postoperative pain control.

Main Methods:

  • A narrative review of literature published between 2010 and 2025.
  • Searches conducted on PubMed using keywords related to pediatric postoperative pain and multimodal analgesia.
  • Adherence to the Narrative Review reporting checklist for study preparation.

Main Results:

  • Evidence supports non-opioid analgesics, regional anesthesia, and standardized perioperative pathways for improved pain control and reduced opioid consumption.
  • Non-pharmacological interventions like distraction, virtual reality, and family engagement enhance pain relief and recovery.
  • Future strategies emphasize integrated models with standardized assessment, individualized therapy, family involvement, and digital follow-up.

Conclusions:

  • Multidisciplinary cooperation is vital for effective pediatric postoperative pain management.
  • Family-centered multimodal strategies and continuous pain monitoring are essential for minimizing opioid side effects.
  • Holistic recovery in children is facilitated by comprehensive and individualized pain management approaches.
Abstract

Keywords:
Pediatric postoperative painfamily-centered caremultimodal analgesianon-pharmacologic interventionopioid-sparing care

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