Related Experiment Videos
Prevalence of Chronic Kidney Disease in Hospitalized Patients in Internal Medicine Wards in Greece: The CKD-HOP Point
Anastasios Tentolouris1, Theodosios Filippatos2, Theodoros Katsikas3
1First Department of Propaedeutic Internal Medicine and Diabetes Center, School of Medicine, National and Kapodistrian University of Athens, Laiko General Hospital, Athens, Greece.
Insights
Chronic kidney disease (CKD) is prevalent in hospitalized Greek adults, particularly the elderly with multiple health issues. Early detection and targeted management are crucial for this high-risk group.
Area of Science:
- Nephrology
- Internal Medicine
- Public Health
Background:
- Chronic kidney disease (CKD) is a significant cause of illness and death.
- A point-prevalence study was conducted in Greece to assess CKD in hospitalized adults.
Purpose of the Study:
- To determine the prevalence and characteristics of CKD in hospitalized internal medicine patients.
- To identify demographic factors, comorbidities, and CKD stages in this population.
Main Methods:
- A nationwide, multicenter study involving 29 Greek hospitals.
- Patients were diagnosed with CKD based on estimated glomerular filtration rate (eGFR) and albumin-to-creatinine ratio (ACR) criteria, or persistent renal abnormalities.
- Data collected included demographics, comorbidities, medication use, CKD stage, and reason for admission.
Main Results:
- The point prevalence of CKD was 17.6% among 1,155 screened patients (203 with CKD).
- The CKD cohort was elderly (mean age 81.2 years) with high rates of hypertension (78.8%), dyslipidemia (53.7%), diabetes (48.3%), and cardiovascular disease (33.0%).
- Most patients had advanced CKD (stages G3b-G4) with a mean eGFR of 31.1 mL/min/1.73 m2; infections were the primary reason for admission (62.6%).
Conclusions:
- CKD is common in hospitalized adults in Greece, especially among the elderly with multiple comorbidities.
- Findings highlight the need for improved early detection, targeted management, and preventive strategies for this high-risk inpatient population.
Background:
Chronic kidney disease (CKD) is a progressive disorder associated with substantial morbidity and mortality. This nationwide, multicenter, point-prevalence study examined the prevalence and characteristics of CKD among adults hospitalized in internal medicine wards across 29 hospitals in Greece.
Methods:
Patients were classified as having CKD if an estimated glomerular filtration rate (GFR) <60 mL/min/1.73 m2 and/or an increased albumin-to-creatinine ratio (ACR >30 mg/g) had been documented at least three months before the index hospitalization. Additional evidence of CKD was considered present when persistent abnormalities in urinalysis, renal biopsy findings, renal imaging, or other paraclinical examinations, persisting for at least three months, confirmed chronic kidney impairment. Demographic data, comorbidities, medication use, CKD stage, and the primary reason for admission were systematically recorded.
Results:
A total of 1,155 patients were screened, of whom 203 met diagnostic criteria for CKD, yielding a point prevalence of 17.6% (95% CI: 15.4-19.9%). The cohort was predominantly elderly (mean age 81.2 years) and exhibited a high burden of multimorbidity, including arterial hypertension (78.8%), dyslipidemia (53.7%), diabetes mellitus (48.3%), and cardiovascular disease (33.0%). Most patients were classified in advanced CKD stages (G3b-G4), with a mean eGFR of 31.1 mL/min/1.73 m2. Infections were the leading cause of admission (62.6%), followed by cardiovascular (23.7%) and gastrointestinal diseases (17.7%).
Conclusion:
CKD is common among hospitalized adults in Greece and is concentrated in elderly patients with substantial comorbidity. These findings underscore the need for targeted management, early detection, and preventive strategies to improve outcomes in this high-risk inpatient population.
Related Concept Videos
Chronic Kidney Disease III: Interprofessional Care
Chronic Kidney Disease I: Introduction
Acute Kidney Injury IV: Diagnostic Studies and Prevention
Chronic Kidney Disease II: Clinical Manifestations
Drug Dosing in Renal Diseases: Estimation of Glomerular Filtration Rate Based on Serum Creatinine Concentration
Acute Kidney Injury III: Clinical Manifestations